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Search Results for " bone erosion "

ターゲット

3

阻害剤

3

天然化合物

3

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T1817 GNF-2 GNF2 SARS-CoV , Bcr-Abl
GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.
T76649 Osteostatin (human)
Osteostatin (human), a fragment derived from parathyroid hormone-related protein (PTHrP) 107-139, effectively promotes bone repair in animal models with bone defects and inhibits bone erosion in cases of inflammatory art...
T81592 Osteostatin PTHrP (107–111)
Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting with bone defects and exhibits efficacy in mitigating bone e...
カタログ番号 製品名 別名 ターゲット
T3777 Praeruptorin A (+)-Praeruptorin A CaMK , NF-κB
Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or...
T3662 Eleutheroside E NF-κB
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...
T4S1419 (±)-Praeruptorin A Praeruptorin A,(-)-Praeruptorin A p38 MAPK , Calcium Channel , Akt
1. (±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Praeruptorin A has the potential to inhibit migration/fusion ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03872 CLEC5A Protein, Rat, Recombinant (His) Rat HEK293
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesio...
TMPY-03928 CLEC5A Protein, Rhesus, Recombinant (mFc) Rhesus HEK293
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesio...
TMPY-03760 CLEC5A Protein, Rhesus, Recombinant (His) Rhesus HEK293
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesio...